Neural crest migration: Patterns, phases and signals
نویسندگان
چکیده
منابع مشابه
Neural crest migration: patterns, phases and signals.
The neural crest is a migratory, multipotent cell type that forms a vast array of vertebrate structures including the craniofacial skeleton and peripheral nervous system (Le Douarin and Kalcheim, 1999). Abnormalities in the ability of neural crest cells to reach precise target sites cause myriad birth defects. Unraveling the mechanisms that generate neural crest migratory patterns is essential ...
متن کاملNeural crest inducing signals.
The formation of the neural crest has been traditionally considered a classic example of secondary induction, where signals form one tissue elicit a response in a competent responding tissue. Interactions of the neural plate with paraxial mesoderm or nonneural ectoderm can generate neural crest. Several signaling pathways converge at the border between neural and nonneural ectoderm where the ne...
متن کاملNeural crest migration: trailblazing ahead
Embryonic cell migration patterns are amazingly complex in the timing and spatial distribution of cells throughout the vertebrate landscape. However, advances in in vivo visualization, cell interrogation, and computational modeling are extracting critical features that underlie the mechanistic nature of these patterns. The focus of this review highlights recent advances in the study of the high...
متن کاملThe neural crest cell cycle is related to phases of migration in the head.
Embryonic cells that migrate long distances must critically balance cell division in order to maintain stream dynamics and population of peripheral targets. Yet details of individual cell division events and how cell cycle is related to phases of migration remain unclear. Here, we examined these questions using the chick cranial neural crest (NC). In vivo time-lapse imaging revealed that a typi...
متن کاملRecycling signals in the neural crest
Vertebrate neural crest cells are multipotent and differentiate into structures that include cartilage and the bones of the face, as well as much of the peripheral nervous system. Understanding how different model vertebrates utilize signaling pathways reiteratively during various stages of neural crest formation and differentiation lends insight into human disorders associated with the neural ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Developmental Biology
سال: 2010
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2010.05.005